Delivery Technologies for Therapeutic Proteins: Assessment and Outlook

Executive Summary and Table of Contents.

Ken Alibek: For the Biodefense

The man who ran the Soviet biological weapons development program now combats germs of war.

Brain Glutamate Concentrations Affect Cocaine Seeking

A possible addiction therapy, built from the ground up.

Gourmet's Delight, A Poisonous Fish Offers Streamlined Genome Project

Preparing to eat a platter of Japanese puffer fish — the gastronomic equivalent of bungie jumping — requires confidence in the chef.

Aiming for the Next Winner

Unusual as it is to start one successful biotech company, it's even more unusual to start several. Which is why serial entrepreneurs make us wonder all the more: How did they do it?

Diagnosing Cancer: A Genomics and Proteomics Approach

Detecting tumors earlier and integrating diagnostics more closely with therapeutic decisions should improve survival.

Types of Clinical Trials

Before a new drug, surgical procedure, or therapy becomes available to the public, it must go through a rigorous testing process and be evaluated by the US Food and Drug Administration (FDA).

Ancient Ancestry

Your ancestors didn't travel to the New World on the Mayflower? Not listed in Burke's Peerage and Baronetage? No worries, mate.

What Women Want: Taking Sex Differences Seriously in Clinical Trials

In clinical trials, sex matters.

Comparing Microarray Data: What Technology is Needed?

DNA microarray analysis is gaining popularity and revealing gene expression patterns that accompany major cancers.

A Cancer Drug with Fan Mail

"I feel so good that sometimes I forget I have leukemia."

Taming the Wolves of Addiction

Anti-addiction therapy attempts to hammer a better world out of bent patients and bad drugs.

Sex Differences and Depression

Although most psychiatric disorders strike men and women with equal impunity, that cannot be said of the most common psychiatric problem, depression.

The Mitochondriacs

Is a drug maker hooked on treating mitochondrial dysfunction a loony, an oddball, a kook, a mitochondriac?